bone morphogenetic protein 4

Product list

Bmp4 is a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates heart development and adipogenesis. Homozygous knockout mice die in utero, while a conditional knockout mouse exhibits defects in heart development. Transgenic mice overexpressing this gene in a neuron-specific manner exhibit a phenotype resembling the rare hereditary connective tissue disease, fibrodysplasia ossificans progressiva.

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Anti-BMP4 Neutralizing Antibody (V3S-0622-YC1083) (CAT#: V3S-0622-YC1083)

Target: BMP4

Host Species: Human

Target Species: Human,

Application: FuncS,

Anti-BMP4 Neutralizing Antibody (V3S-0622-YC1084) (CAT#: V3S-0622-YC1084)

Target: BMP4

Host Species: Mouse

Target Species: Human,

Application: FuncS,

Anti-BMP4 Neutralizing Antibody (V3S-0622-YC1085) (CAT#: V3S-0622-YC1085)

Target: BMP4

Host Species: Mouse

Target Species: Human,

Application: FuncS,

Anti-BMP4 Neutralizing Antibody (V3S-0822-YC414) (CAT#: V3S-0822-YC414)

Target: BMP4

Host Species: Mouse

Target Species: Human,

Application: ELISA,Neut,WB,

Anti-BMP4 Neutralizing Antibody (V3S-0822-YC415) (CAT#: V3S-0822-YC415)

Target: BMP4

Host Species: Mouse

Target Species: Human,

Application: Neut,WB,

Anti-BMP4 Neutralizing Antibody (V3S-0822-YC416) (CAT#: V3S-0822-YC416)

Target: BMP4

Host Species: Mouse

Target Species: Human,

Application: Neut,WB,ELISA,

Anti-BMP4 Neutralizing Antibody (V3S-0822-YC417) (CAT#: V3S-0822-YC417)

Target: BMP4

Host Species: Mouse

Target Species: Human,

Application: ELISA,WB,IHC,Neut,

Anti-Bmp4 (aa 293-408) Neutralizing Antibody (V3S-0822-YC418) (CAT#: V3S-0822-YC418)

Target: Bmp4

Host Species: Mouse

Target Species: Mouse,

Application: Neut,

For research use only, not directly for clinical use.

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