Bone Morphogenetic Protein Receptor Type 1B

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Bone Morphogenetic Protein Receptor Type 1B belongs to the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension.

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Recombinant Anti-BMPR1B Antibody (V3S-0522-YC2999) (CAT#: V3S-0522-YC2999)

Target: BMPR1B

Host Species: Mouse

Target Species: Human,

Application: ELISA,