interleukin 18 receptor accessory protein

Product list

IL18RAP is an accessory subunit of the heterodimeric receptor for interleukin 18 (IL18), a proinflammatory cytokine involved in inducing cell-mediated immunity. This protein enhances the IL18-binding activity of the IL18 receptor and plays a role in signaling by IL18. Mutations in this gene are associated with Crohn's disease and inflammatory bowel disease, and susceptibility to celiac disease and leprosy. Alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.

Show More Close

Inquiry

Anti-IL18RAP Neutralizing Antibody (V3S-0822-YC1616) (CAT#: V3S-0822-YC1616)

Target: IL18RAP

Host Species: Mouse

Target Species: Human,

Application: Neut,WB,