Interleukin 27

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IL27 is one of the subunits of a heterodimeric cytokine complex. This protein is related to interleukin 12A (IL12A). It interacts with Epstein-Barr virus induced gene 3 (EBI3), a protein similar to interleukin 12B (IL12B), and forms a complex that has been shown to drive rapid expansion of naive but not memory CD4(+) T cells. The complex is also found to synergize strongly with interleukin 12 to trigger interferon gamma (IFNG) production of naive CD4(+) T cells. The biological effects of this cytokine are mediated by the class I cytokine receptor (WSX1/TCRR).

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Recombinant Anti-IL27 Antibody (V3S-0622-YC4721) (CAT#: V3S-0622-YC4721)

Target: IL27

Host Species: Mouse

Target Species: Human,

Application: ELISA,