LEP Specific Neutra™ Antibody Products
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Are you currently facing challenges in accurately quantifying leptin levels in diverse biological samples, or struggling to find highly specific reagents for your metabolic and obesity research? Our LEP (leptin) Specific Antibody Products from Creative Biolabs provide the precision and reliability you need to overcome these obstacles. We help you obtain high-quality data and accelerate your drug discovery and diagnostic projects through our meticulously validated antibody products and expert support.
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Introduction of LEP
Leptin is a protein hormone secreted primarily by fat cells, acting as a key regulator of energy balance. It signals to the brain's hypothalamus about the body's energy stores, which in turn helps control appetite and metabolism. This function has led to it being known as the "satiety hormone." Leptin also plays a role in various other physiological processes, including glucose and lipid metabolism. A common issue is leptin resistance, where the body fails to respond to high leptin levels, often contributing to obesity and related metabolic disorders like type 2 diabetes and non-alcoholic fatty liver disease (NAFLD). Accurate leptin detection is therefore critical for understanding these complex interactions.
Fig.1 Leptin signaling.1
Our Anti-LEP Antibody Products
Antibodies against leptin are powerful tools for unraveling metabolic signaling. Designed for high affinity and selectivity, they are used across various scientific applications, from basic research to diagnostics. Key applications of these antibodies include quantitative ELISA assays for measuring circulating leptin, Western blotting for protein expression studies, and Immunofluorescence and Immunohistochemistry to visualize leptin's localization in cells and tissues. These tools are fundamental for understanding leptin's normal functions and its role in disease.
Why Choose Us?
Creative Biolabs is a leader in providing scientifically validated antibody products. Our LEP (leptin) specific antibodies are meticulously developed and tested for unparalleled performance. We are committed to your success, which is backed by several key advantages:
- Unparalleled Specificity: Our antibodies are engineered for exceptional specificity, minimizing cross-reactivity and ensuring reliable results.
- Proven High Sensitivity: We offer products with high sensitivity, enabling the detection of leptin at low concentrations for accurate quantification.
- Broad Application Versatility: Our products are validated for ELISA, Western Blotting, IHC, and IF, providing versatile tools for your research.
- Rigorous Quality Control: Every antibody batch undergoes stringent quality control to guarantee lot-to-lot consistency.
FAQs
Q: How do your leptin antibodies ensure accurate quantification in samples with potentially interfering proteins?
A: Our antibodies are developed with a focus on high specificity to the leptin epitope. They undergo rigorous screening and validation against potential cross-reacting targets and are optimized for specific assay formats like ELISA to minimize background noise and ensure that you are measuring leptin and only leptin.
Q: Can these products be used to detect leptin from different species?
A: Yes, we offer a range of products with validated reactivity across multiple species, including human, mouse, and rat. This allows researchers to confidently conduct comparative studies and apply our tools to various animal models.
Q: What is the recommended storage and handling protocol for the leptin antibodies?
A: To maintain optimal activity, it is recommended to store our antibodies at −20 ℃ or −80 ℃ upon receipt. We provide detailed storage and handling instructions with each product to ensure longevity and consistent performance for your experiments.
Q: Are these antibodies suitable for detecting both full-length and truncated forms of leptin?
A: Our product line includes antibodies that target different epitopes on the leptin protein. This enables you to choose the most suitable antibody for your specific research needs, whether you are interested in detecting the full-length protein or specific truncated forms.
Q: How do these antibodies contribute to high-throughput screening projects?
A: The high specificity and sensitivity of our antibodies, combined with their robust performance in high-throughput formats like ELISA, make them ideal for screening large numbers of samples. This helps accelerate initial research and quickly identify samples of interest for further, more detailed analysis.
Creative Biolabs' LEP (leptin) Specific Antibody Products are an essential resource for researchers and clinicians working on metabolic diseases, obesity, and related disorders. We provide the high-quality, validated reagents you need to achieve accurate, reproducible, and impactful results. Our commitment to scientific rigor and customer success ensures you have a reliable partner for your most critical projects.
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REFERENCE
- Obradovic, Milan et al. "Leptin and Obesity: Role and Clinical Implication." Frontiers in endocrinology vol. 12 585887. 18 May. 2021, doi:10.3389/fendo.2021.585887, Distributed under Open Access license CC BY 4.0, without modification. https://doi.org/10.3389/fendo.2021.585887
