leukocyte immunoglobulin like receptor B2

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LILRB2 is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity.
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Anti-LILRB2 Neutralizing Antibody (V3S-0822-YC2062) (CAT#: V3S-0822-YC2062)

Target: LILRB2

Host Species: Mouse

Target Species: Human,

Application: WB,FC,CyTOF,Neut,

For research use only, not directly for clinical use.

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