Protective antigen

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The lethality of anthrax is primarily the result of the effects of anthrax toxin, which has 3 components: a receptor-binding protein known as PA ("protective antigen") and 2 catalytic proteins known as LF ("lethal factor") and EF ("edema factor"). Entry of the toxins into the cell is initiated by rapid binding of the 83-kDa PA to the cellular receptor, whereupon a furinlike protease cleaves the bound PA into an N-terminal PA20 (20-kDa protein) and a C-terminal PA63 (63-kDa protein).

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Anti-PA Neutralizing Antibody (V3S-0622-YC416) (CAT#: V3S-0622-YC416)

Target: PA

Host Species: Human

Target Species: Bacillus anthracis,

Application: ELISA,Neut,

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Anti-PA (aa 596-735) Neutralizing Antibody (V3S-0522-YC7145) (CAT#: V3S-0522-YC7145)

Target: PA

Host Species: Mouse

Target Species: Bacillus anthracis,

Application: Neut,

For research use only, not directly for clinical use.