Receptor-like tyrosine kinase

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The protein encoded by this gene is an atypical member of the family of growth factor receptor protein tyrosine kinases, differing from other members at a number of conserved residues in the activation and nucleotide binding domains. This gene product belongs to a subfamily whose members do not appear to be regulated by phosphorylation in the activation segment. It has been suggested that mediation of biological activity by recruitment of a signaling-competent auxiliary protein may occur through an as yet uncharacterized mechanism. The encoded protein has a leucine-rich extracellular domain with a WIF-type Wnt binding region, a single transmembrane domain, and an intracellular tyrosine kinase domain. This protein is involved in stimulating Wnt signaling pathways such as the regulation of axon pathfinding.
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Anti-RYK Neutralizing Antibody (V3S-0622-YC5303) (CAT#: V3S-0622-YC5303)

Target: RYK

Host Species: Human

Target Species: Human,

Application: WB,ELISA,Block. IHC,IP,FC,

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Anti-RYK (aa 90-183) Neutralizing Antibody (V3S-0522-YC2590) (CAT#: V3S-0522-YC2590)

Target: RYK

Host Species: Mouse

Target Species: Human,

Application: Inhib,

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Anti-RYK (aa 90-183) Neutralizing Antibody (V3S-0522-YC2591) (CAT#: V3S-0522-YC2591)

Target: RYK

Host Species: Mouse

Target Species: Human,

Application: Inhib,

For research use only, not directly for clinical use.


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