| Description | This product is a cell-penetrating nucleolytic antibody that specifically recognizes DNA. The antibody 5C6 is a nucleolytic lupus autoantibody and can degrade both single-stranded and double-stranded plasmid DNA. It can be used as an agent targeted towards DNA repair-deficient malignancies. |
| Clonality | Monoclonal |
| Host Species | Mouse |
| Target Species | Non-species dependence |
| Isotype | IgG2a kappa |
| Expression Species | HEK293F or CHO |
| Conjugation | None |
| Purity | >95%, determined by SDS-PAGE and SEC-HPLC |
| Endotoxin | <1 EU/mg |
| Purification | Protein G affinity purified |
| Sterility | 0.2 μM filtered |
| Formulation | PBS, pH 7.4 |
| Preservation | No preservatives |
| Stabilizer | No stabilizers |
| Storage | Store at 4°C within a week. For longer storage, aliquot and store at -20°C. |
| Application | FuncS |
| Application Notes | The antibody is recommended for detection of DNA by FuncS assay. |
| ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
| WB | Western Blot Protocol |
| FC | Flow Cytometry Protocol |
| Target | DNA |
| Alternative Name | Deoxyribonucleic acid |
| Research Area | Cell Biology |
