BSG Specific Recomb™ Antibody (V3S-0224-CJ17), Human IgG (CAT#: V3S-0224-CJ17)

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Datasheet

MSDS

COA

Summary
Property
Applications
Protocols
Target
Virus Background

Summary

Description Humanized monoclonal antibody hPPAT-082-01 specifically binds to human BSG (basigin), also known as CD147. This antibody was also found to react with cynomolgus monkey. It may have anti-tumor activity in a xenograft mouse model.
Clonality Monoclonal
Host Species Human
Target Species Human, Cynomolgus
Isotype Human IgG

Property

Expression Species HEK293F or CHO
Conjugation None
Purity >95%, determined by SDS-PAGE and SEC-HPLC
Endotoxin <1 EU/mg
Purification Protein A affinity purified
Sterility 0.2 μM filtered
Formulation PBS, pH 7.4
Preservation No preservatives
Stabilizer No stabilizers
Storage Store at 4°C within a week. For longer storage, aliquot and store at -20°C.

Applications

Application ELISA; FC; FuncS
Application Notes The binding specificity of antibody hPPAT-082-01 to human and monkey BSG can be determined by ELISA and Flow Cytometry.

Protocols

ELISA Enzyme-Linked Immunosorbent Assay Protocol
WB Western Blot Protocol
FC Flow Cytometry Protocol

Target

Target BSG
Alternative Name 5F7; CD147; EMMPRIN; EMPRIN; HAb18G; OK; TCSF
Gene ID 682
UniProt P35613
Related pathway Transport of inorganic cations/anions and amino acids/oligopeptides; Pyruvate metabolism
Research Area Immunology; Neuroscience
Related Disease Ameloblastoma; Measles

Virus Background

Post Translational Modification Isoform 2: N-glycosylated.
Isoform 3: N-glycosylated.
Isoform 4: N-glycosylated.
For research use only, not directly for clinical use.
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