| Description | 6G11 is a fully human monoclonal antibody that can be readily detected in the sera of mice. However, it is inherently immunogenic. The affinity of 6G11 for selected hFcγRIIB monoclonal antibodies is measured at 26.4 nM. In NK cell effectors that express high- or low-affinity variants of hFcγRIIIA, 6G11 demonstrated greater potency than rituximab in inducing cell death. |
| Clonality | Monoclonal |
| Host Species | Human |
| Target Species | Human |
| Affinity | 26.4 nM |
| Isotype | IgG1 |
| Expression Species | HEK293F or CHO cell line |
| Conjugation | Unconjugated |
| Purity | >95% |
| Endotoxin | <1 EU/mg |
| Form | Liquid |
| Purification | Protein A purified |
| Sterility | 0.2 μM filtered |
| Formulation | PBS, pH 7.4 |
| Preservation | No preservatives |
| Stabilizer | No stabilizers |
| Storage | Store at 4°C within one or two weeks. Store at -20°C for long term. Avoid repeated freeze/thaw cycles. Refer to the COA file for specifics. |
| Application | ELISA |
| ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
| WB | Western Blot Protocol |
| FC | Flow Cytometry Protocol |
| Target | FCGR2B |
| Alternative Name | Fc Fragment Of IgG Receptor IIb; Fc Fragment Of IgG, Low Affinity IIb, Receptor For (CD32); Fc Fragment Of IgG, Low Affinity IIb, Receptor (CD32); Fc Gamma Receptor IIb; IgG Fc Receptor II-B; Fc-Gamma RII-B; Fc-Gamma-RIIb; FcRII-B; CDw32; IGFR2 |
| Gene ID | 2213 |
| UniProt | P31994 |
| Research Area | Immunology; Stem Cell |
