| Description | The humanized version of C10-2 (hC10-2) has the ability to remove a greater amount of aggregated Tau protein found in Alzheimer's brain extracts. hC10-2 effectively reduces the presence of hyperphosphorylated tau and eliminates 99.5% of tau aggregates. |
| Clonality | Monoclonal |
| Host Species | Human |
| Target Species | Human |
| Immunogen | Phosphorylated residue 396 of human tau |
| Epitope | Tau (pS396) |
| Isotype | IgG |
| Expression Species | HEK293F or CHO cell line |
| Conjugation | Unconjugated |
| Purity | >95% |
| Endotoxin | <1 EU/mg |
| Form | Liquid |
| Purification | Protein A purified |
| Sterility | 0.2 μM filtered |
| Formulation | PBS, pH 7.4 |
| Preservation | No preservatives |
| Stabilizer | No stabilizers |
| Storage | Store at 4°C within one or two weeks. Store at -20°C for long term. Avoid repeated freeze/thaw cycles. Refer to the COA file for specifics. |
| Application | ELISA; RIA; WB |
| Application Notes | hC10-2 effectively reduces the presence of hyperphosphorylated tau and eliminates 99.5% of tau aggregates. |
| ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
| WB | Western Blot Protocol |
| FC | Flow Cytometry Protocol |
| Target | MAPT (pS396) |
| Alternative Name | Microtubule Associated Protein Tau; G Protein Beta1/Gamma2 Subunit-Interacting Factor 1; Protein Phosphatase 1, Regulatory Subunit 103; Neurofibrillary Tangle Protein; Paired Helical Filament-Tau; PHF-Tau; MAPTL; MTBT1; TAU; MAPT (pS396); Microtubule Associated Protein Tau (pS396); pS396 |
| Gene ID | 4137 |
| UniProt | P10636 |
| Research Area | Neuroscience; Signal Pathway |
