Synoviolin 1
Product list
This gene encodes a protein involved in endoplasmic reticulum (ER)-associated degradation. The encoded protein removes unfolded proteins, accumulated during ER stress, by retrograde transport to the cytosol from the ER. This protein also uses the ubiquitin-proteasome system for additional degradation of unfolded proteins. Diseases associated with SYVN1 include Wolfram Syndrome 1 and Wolfram Syndrome. Among its related pathways are Metabolism of proteins and Calnexin/calreticulin cycle.