transforming growth factor, beta 2

Product list

Tgfb2 is a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGF-beta family members. Mice lacking a functional copy of this gene display developmental defects in multiple organs and perinatal lethality. Heterozygous mutant mice exhibit aortic root aneurysm. This gene encodes multiple isoforms that may undergo similar proteolytic processing.

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Anti-TGFB2 Neutralizing Antibody (V3S-0622-YC2644) (CAT#: V3S-0622-YC2644)

Target: TGFB2

Host Species: Human

Target Species: Human,

Application: ELISA,IP,FC,FuncS,Neut,IF,ICC,

Recombinant Anti-TGFB2 Antibody (V3S-0522-YC2118) (CAT#: V3S-0522-YC2118)

Target: TGFB2

Host Species: Human

Target Species: Human, Mouse,

Application: ELISA,FuncS,

Recombinant Anti-TGFB2 Antibody (V3S-0522-YC2119) (CAT#: V3S-0522-YC2119)

Target: TGFB2

Host Species: Human

Target Species: Human, Mouse,

Application: ELISA,FuncS,

Recombinant Anti-TGFB2 Antibody (V3S-0522-YC2120) (CAT#: V3S-0522-YC2120)

Target: TGFB2

Host Species: Human

Target Species: Human, Mouse,

Application: ELISA,FuncS,

Recombinant Anti-TGFB2 Antibody (V3S-0522-YC2121) (CAT#: V3S-0522-YC2121)

Target: TGFB2

Host Species: Human

Target Species: Human, Mouse,

Application: ELISA,FuncS,

Recombinant Anti-TGFB2 Antibody (V3S-0522-YC2122) (CAT#: V3S-0522-YC2122)

Target: TGFB2

Host Species: Human

Target Species: Human, Mouse,

Application: ELISA,FuncS,

Recombinant Anti-TGFB2 Antibody (V3S-0522-YC2123) (CAT#: V3S-0522-YC2123)

Target: TGFB2

Host Species: Human

Target Species: Human, Mouse,

Application: ELISA,FuncS,

Anti-Tgfb2 Neutralizing Antibody (V3S-0822-YC2381) (CAT#: V3S-0822-YC2381)

Target: Tgfb2

Host Species: Rat

Target Species: Mouse,

Application: IHC,Neut,WB,

Anti-Tgfb2 Neutralizing Antibody (V3S-0822-YC2382) (CAT#: V3S-0822-YC2382)

Target: Tgfb2

Host Species: Rat

Target Species: Mouse,

Application: Neut,

For research use only, not directly for clinical use.

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