| Description | The antibody against amyloid plaques was derived by immunizing with a 16 amino acid peptide of beta-amnyloid (acids 1-16) conjugated to KLH. The antibody has specific activity to Aβ in preventing its toxic affects on PC12 cells. |
| Clonality | Monoclonal |
| Host Species | Mouse |
| Target Species | Human |
| Immunogen | A 16 amino acid peptide of beta-amyloid (acids Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys) conjugated to KLH. |
| Epitope | The epitope is located in amino acids Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys. |
| Affinity | The KD value, 0.1 uM, were determined using 2:1 kinetics of binding of analyte (BSA-cSNK). |
| Isotype | IgM |
| Expression Species | HEK293F or CHO |
| Conjugation | None |
| Purity | >95%, determined by SDS-PAGE and SEC-HPLC |
| Endotoxin | <1 EU/mg |
| Purification | Protein G affinity purified |
| Sterility | 0.2 μM filtered |
| Formulation | PBS, pH 7.4 |
| Preservation | No preservatives |
| Stabilizer | No stabilizers |
| Storage | Store at 4°C within a week. For longer storage, aliquot and store at -20°C. |
| Application | ELISA |
| Application Notes | The antibody is recommended for detection of APP by ELISA assay. |
| ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
| WB | Western Blot Protocol |
| FC | Flow Cytometry Protocol |
| Target | APP |
| Alternative Name | Amyloid Beta Precursor Protein; Amyloid Beta (A4) Precursor Protein; Alzheimer Disease Amyloid Protein; Cerebral Vascular Amyloid Peptide; Amyloid Precursor Protein; Peptidase Nexin-II; Protease Nexin-II; PreA4; PN-II; ABPP; APPI; CVAP; AD1; Beta-Amyloid Precursor Protein; 508F(Fv) |
| Gene ID | 351 |
| UniProt | P05067 |
| Research Area | Neuroscience |
