Description | This product is a human-mouse chimeric neutralizing monoclonal antibody, which effectively neutralize anthrax lethal toxin (EC50 = 1.68 nM) as proved by in vitro experiment and animal experiment. |
Clonality | Monoclonal |
Host Species | Human |
Target Species | Bacillus anthracis |
Isotype | IgG |
Expression Species | HEK293F or CHO |
Conjugation | None |
Purity | >95%, determined by SDS-PAGE and SEC-HPLC |
Endotoxin | <1 EU/mg |
Purification | Protein A affinity purified |
Sterility | 0.2 μM filtered |
Formulation | PBS, pH 7.4 |
Preservation | No preservatives |
Stabilizer | No stabilizers |
Storage | Store at 4°C within a week. For longer storage, aliquot and store at -20°C. |
Application | ELISA; Neut; FuncS |
Application Notes | HcLF8 antibody can be protected cell effectively, the necrocytosis of avoiding anthrax toxin to cause, median effective dose EC50 = 1.68 nM. |
ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
WB | Western Blot Protocol |
FC | Flow Cytometry Protocol |
Target | Anthrax LF |
Alternative Name | Anthrax lethal factor; LF |
Research Area | Infectious Disease |