| Description | This product is a human monoclonal antibody that reacts with ANTXR1. The ANTXR1 antibody was effective at slowing tumor growth in the UACC melanoma model. A combination of the mAb and paclitaxel is effective against H460 cancer cells in the xenograft model, and that the combination is more effective than either agent alone. |
| Clonality | Monoclonal |
| Host Species | Human |
| Target Species | Human, Mouse |
| Affinity | 3.744 nM for mouse and 1.57 nM for human |
| Isotype | IgG1 |
| Expression Species | HEK293F or CHO |
| Conjugation | None |
| Purity | >95%, determined by SDS-PAGE and SEC-HPLC |
| Endotoxin | <1 EU/mg |
| Purification | Protein A affinity purified |
| Sterility | 0.2 μM filtered |
| Formulation | PBS, pH 7.4 |
| Preservation | No preservatives |
| Stabilizer | No stabilizers |
| Storage | Store at 4°C within a week. For longer storage, aliquot and store at -20°C. |
| Application | FuncS |
| Application Notes | The antibody is recommended for detection of ANTXR1 by FuncS assay. |
| ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
| WB | Western Blot Protocol |
| FC | Flow Cytometry Protocol |
