| Description | This product is a recombinant human antibody provided by CreativeBiolabs. The antibody is specific for Calcitonin Related Polypeptide Alpha, this gene encodes the peptide hormones calcitonin, calcitonin gene-related peptide and katacalcin by tissue-specific alternative RNA splicing of the gene transcripts and cleavage of inactive precursor proteins. It can be used for CALCA detection in Enzyme-Linked Immunosorbent Assay. It was expressed in mammalian cells (293F or CHO) with antibody encoding genes and purified by affinity chromatography. Each lot of this antibody is quality control tested by SDS-PAGE and SEC-HPLC analysis. For highly sensitive assays, we recommend the ultrapurified form of the product, which has a lower endotoxin limit than standard antibody, less than 1 EU/mg or even 0.1 EU/mg. |
| Clonality | Monoclonal |
| Host Species | Human |
| Target Species | Human |
| Isotype | IgG kappa |
| Expression Species | HEK293F or CHO Cell line |
| Conjugation | Unconjugated, also available for Biotin, HRP, FITC and PE-labeled form. |
| Purity | >95%, determined by SDS-PAGE and SEC-HPLC |
| Endotoxin | <1 EU/mg, determined by LAL method |
| Purification | Purified with Protein A or G affinity chromatography |
| Sterility | 0.2 μM filtered |
| Formulation | PBS, pH 7.4 |
| Preservation | No preservatives |
| Stabilizer | No stabilizers |
| Storage | Store at 4°C within one or two weeks. Store at -20°C for long term. Avoid repeated freeze/thaw cycles. Refer to the COA file for specifics. |
| Application | ELISA |
| ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
| WB | Western Blot Protocol |
| FC | Flow Cytometry Protocol |
| Target | CALCA |
| Alternative Name | Calcitonin Related Polypeptide Alpha; Calcitonin Gene-Related Peptide I; Alpha-Type CGRP; Calcitonin 1; Calcitonin; CGRP-I; CALC1; Calcitonin/Calcitonin-Related Polypeptide, Alpha |
| Gene ID | 796 |
| UniProt | P01258 |
| Research Area | Cell Biology |
| Related Disease | Allergic dermatitis, Psoriasis, Encephalitis: brain trauma, Epilepsy, Neurodegenerative disease, Skin disease including pruritis, Neurogenic cutaneous redness skin rosaceousness and erythema, Inflammatory bowel disease |
