| Description | This product is a recombinant human antibody provided by CreativeBiolabs. The antibody is specific for Fc Fragment Of IgG Receptor IIIa, this gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. It can be used for FCGR3A detection in Cytotoxicity Assay. It was expressed in mammalian cells (293F or CHO) with antibody encoding genes and purified by affinity chromatography. Each lot of this antibody is quality control tested by SDS-PAGE and SEC-HPLC analysis. For highly sensitive assays, we recommend the ultrapurified form of the product, which has a lower endotoxin limit than standard antibody, less than 1 EU/mg or even 0.1 EU/mg. |
| Clonality | Monoclonal |
| Host Species | Human |
| Target Species | Human |
| Affinity | The affinity is in nanomolar range, about 9.3 nM, determined by surface plasmon resonance. |
| Isotype | IgG1 |
| Expression Species | HEK293F or CHO Cell line |
| Conjugation | Unconjugated, also available for Biotin, HRP, FITC and PE-labeled form. |
| Purity | >95%, determined by SDS-PAGE and SEC-HPLC |
| Endotoxin | <1 EU/mg, determined by LAL method |
| Purification | Purified with Protein A or G affinity chromatography |
| Sterility | 0.2 μM filtered |
| Formulation | PBS, pH 7.4 |
| Preservation | No preservatives |
| Stabilizer | No stabilizers |
| Storage | Store at 4°C within one or two weeks. Store at -20°C for long term. Avoid repeated freeze/thaw cycles. Refer to the COA file for specifics. |
| Application | Cyt |
| ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
| WB | Western Blot Protocol |
| FC | Flow Cytometry Protocol |
| Target | FCGR3A |
| Alternative Name | Fc Fragment Of IgG Receptor IIIa; Fc Fragment Of IgG, Low Affinity IIIa, Receptor (CD16a); Fc Gamma Receptor IIIa; IgG Fc Receptor III-2; Fc-Gamma RIII-Alpha; Fc-Gamma RIIIa; Fc-Gamma RIII; CD16a Antigen; FCRIIIA; FCR-10; FCRIII; FCGR3; CD16A; IGFR3; FCG3 |
| Gene ID | 2214 |
| UniProt | P08637 |
| Research Area | Cardiovascular; Signal Pathway |
