| Description | The clone ZIKV-116 binds to E, DIII and E-FLM. mAb ZIKV-116 binds to an epitope involving residues T309, E393, and K394 on the DIII (DIII-LR) side ridge, which was confirmed by ELISA. Mutations A310E and T335K in DIII-LR reduce binding to DIII. ZIKV-116 was effective against four of the five strains but was inactive against the original African strain MR 766. ZIKV-116 neutralizes ZIKV infection. |
| Clonality | Monoclonal |
| Host Species | Human |
| Target Species | Zika Virus (ZIKV) |
| Isotype | IgG1, kappa |
| Expression Species | HEK293F or CHO cell line |
| Conjugation | Unconjugated |
| Purity | >95% |
| Endotoxin | <1 EU/mg |
| Form | Liquid |
| Purification | Protein A purified |
| Sterility | 0.2 μM filtered |
| Formulation | PBS, pH 7.4 |
| Preservation | No preservatives |
| Stabilizer | No stabilizers |
| Storage | Store at 4°C within one or two weeks. Store at -20°C for long term. Avoid repeated freeze/thaw cycles. Refer to the COA file for specifics. |
| Application | ELISA; WB; Neut |
| ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
| WB | Western Blot Protocol |
| FC | Flow Cytometry Protocol |
| Target | ZIKV |
| Alternative Name | Zika virus; ZIKV |
| Research Area | Microbiology |
