Recombinant Anti-CD274 Antibody (V3S-0723-FY202) (CAT#: V3S-0723-FY202)

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  • fig1

Datasheet

MSDS

COA

Summary
Property
Applications
Protocols
Target

Summary

Description The full human monoclonal antibody binds to PD-L1 with a KD value of 1.82 nM. This antibody can effectively inhibit the PD-1 protein and its PD-L1 complexes in vitro, and this inhibition is dose-dependent. The IC50 value of Q1-43 is 50.05 ng/mL.
Clonality Monoclonal
Host Species Human
Target Species Human
Affinity 1.82 nM
Isotype IgG1

Property

Expression Species HEK293F or CHO cell line
Conjugation Unconjugated
Purity >95%
Endotoxin <1 EU/mg
Form Liquid
Purification Protein A purified
Sterility 0.2 μM filtered
Formulation PBS, pH 7.4
Preservation No preservatives
Stabilizer No stabilizers
Storage Store at 4°C within one or two weeks. Store at -20°C for long term. Avoid repeated freeze/thaw cycles. Refer to the COA file for specifics.

Applications

Application ELISA
Application Notes Inhibition assay: The IC50 value of Q1-43 is 50.05 ng/mL.

Protocols

ELISA Enzyme-Linked Immunosorbent Assay Protocol
WB Western Blot Protocol
FC Flow Cytometry Protocol

Target

Target CD274
Alternative Name B7-H; B7H1; PDL1; PD-L1; hPD-L1; PDCD1L1; PDCD1LG1
Gene ID 29126
UniProt Q9NZQ7
Research Area Immunology
For research use only, not directly for clinical use.
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