Description | CD40 antibody is a fully human IgG2 isotype antibody. The anti-CD40 antibody specifically binds to and activates human CD4, with a binding affinity KD value of 10 nM for the human CD40 antigen. |
Clonality | Monoclonal |
Host Species | Human |
Target Species | Human |
Affinity | KD = 0.4 nM |
Isotype | Human IgG2 |
Expression Species | HEK293F or CHO |
Purity | >95%, determined by SDS-PAGE and SEC-HPLC |
Endotoxin | <1 EU/mg |
Purification | Protein A affinity purified |
Sterility | 0.2 μM filtered |
Formulation | PBS, pH 7.4 |
Preservation | No preservatives |
Stabilizer | No stabilizers |
Storage | Store at 4°C within a week. For longer storage, aliquot and store at -20°C. |
Application | Inhib |
ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
WB | Western Blot Protocol |
FC | Flow Cytometry Protocol |
Target | CD40 |
Alternative Name | CD40 Molecule; CD40 Molecule, TNF Receptor Superfamily Member 5; CD40L Receptor; TNFRSF5; CDW40; Bp50; Tumor Necrosis Factor Receptor Superfamily, Member 5 |
Gene ID | 958 |
UniProt | P25942 |
Related pathway | JNK/SAPK and NF-κB signaling pathways |
Research Area | Cancer Research; Signal Pathway |
Related Disease | Cancer |