Description | This product is an inhibitory antibody that recognizes IAV H7N9 NA. It exhibits strong inhibition of NA activity, similar strong inhibition to zanamivir on the NA cleavage activity of 4-MU-NANA, and almost complete inhibition of α2-3 and α2-6 linked sialic acid glycosides NA activity. |
Clonality | Monoclonal |
Host Species | Human |
Target Species | Influenzavirus A Subtype H7N9 |
Epitope | AA 37-468 |
Isotype | Human IgG |
Expression Species | HEK293F or CHO |
Conjugation | None |
Purity | >95%, determined by SDS-PAGE and SEC-HPLC |
Endotoxin | <1 EU/mg |
Purification | Protein A purified |
Sterility | 0.2 μM filtered |
Formulation | PBS, pH 7.4 |
Preservation | No preservatives |
Stabilizer | No stabilizers |
Storage | Store at 4°C within a week. For longer storage, aliquot and store at -20°C. |
Application | ELISA; Inhib |
Application Notes | NA-73 almost completely inhibited NA activity on α2-3 and α2-6 linked sialoside, whereas NA-63 and NA-45 showed significant but incomplete inhibition. NA-73 completely blocks the active site entrance |
ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
WB | Western Blot Protocol |
FC | Flow Cytometry Protocol |
Target | IAV H7N9 NA |
Alternative Name | Influenza A virus H7N9 Neuraminidase; Influenza A virus; H7N9; Neuraminidase; NA; IAV; N9; Influenza A virus subtype H7N9 |
Research Area | Microbiology |