Recombinant Anti-PRLR (ECD domain) Antibody (V3S-0723-FY110) (CAT#: V3S-0723-FY110)

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Datasheet

MSDS

COA

Summary
Property
Applications
Protocols
Target

Summary

Description 005-C04 is a recombinant human antibody that recognizes human PRLR. The antibody 005-C04 reacts with the extracellular domain of PRLR. It is cross reactive with mouse. The clone 005-C04 inhibited phosphorylation of STAT5 in T47D cells in a dose-dependent manner. Antibody 005-C04 showed sufficient cross-reactivity with the murine prolactin receptor and was therefore the only antibody available for the murine in vivo model.
Clonality Monoclonal
Host Species Human
Target Species Human, Mouse
Epitope Extracellular domain
Isotype IgG1

Property

Expression Species HEK293F or CHO cell line
Conjugation Unconjugated
Purity >95%
Endotoxin <1 EU/mg
Form Liquid
Purification Protein A purified
Sterility 0.2 μM filtered
Formulation PBS, pH 7.4
Preservation No preservatives
Stabilizer No stabilizers
Storage Store at 4°C within one or two weeks. Store at -20°C for long term. Avoid repeated freeze/thaw cycles. Refer to the COA file for specifics.

Applications

Application ELISA; FC; Inhib

Protocols

ELISA Enzyme-Linked Immunosorbent Assay Protocol
WB Western Blot Protocol
FC Flow Cytometry Protocol

Target

Target PRLR
Alternative Name HPRL; MFAB; hPRLrI; RI-PRLR; prolactin receptor; hPRL receptor; secreted prolactin binding protein
Gene ID 5618
UniProt P16471
Research Area Signal Pathway
For research use only, not directly for clinical use.
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