| Description |
This product is a recombinant human antibody provided by CreativeBiolabs. The antibody is specific for Activin A Receptor Type 2B, Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. It can be used for ACVR2B detection in Enzyme-Linked Immunosorbent Assay. It was expressed in mammalian cells (293F or CHO) with antibody encoding genes and purified by affinity chromatography. Each lot of this antibody is quality control tested by SDS-PAGE and SEC-HPLC analysis. For highly sensitive assays, we recommend the ultrapurified form of the product, which has a lower endotoxin limit than standard antibody, less than 1 EU/mg or even 0.1 EU/mg. |
| Clonality |
Monoclonal |
| Host Species |
Human |
| Target Species |
Human |
| Immunogen |
Human activin receptor type-2b (ActRIIB) |
| Epitope |
The epitope is in the AA 21-120 of ACVR2B. |
| Affinity |
The affinity is in picomolar range, about 3.8 pM, determined by surface plasmon resonance. |
| Isotype |
IgG2 |
