| Description | This product is a BBB-selective antibody. The blood-brain barrier (BBB) possesses a unique vascular phenotype that is induced by neighboring cells such as pericytes, astrocytes and neurons that together form the neurovascular unit. The clone 15 exhibited brain endothelial cell selectivity in tissue culture. The results showed that clone 15 selectively bound to rat brain vessels in vivo with substantial brain vascular selectivity as judged by differential vascular immune-labeling in tissue sections. |
| Clonality | Monoclonal |
| Host Species | Human |
| Target Species | Rat |
| Isotype | IgG |
| Expression Species | HEK293F or CHO |
| Conjugation | None |
| Purity | >95%, determined by SDS-PAGE and SEC-HPLC |
| Endotoxin | <1 EU/mg |
| Purification | Protein A affinity purified |
| Sterility | 0.2 μM filtered |
| Formulation | PBS, pH 7.4 |
| Preservation | No preservatives |
| Stabilizer | No stabilizers |
| Storage | Store at 4°C within a week. For longer storage, aliquot and store at -20°C. |
| Application | ELISA; ICC; FC; IHC |
| Application Notes | The antibody is recommended for detection of Blood-brain barrier by ELISA, ICC, FC, IHC (1/20-1/200) assays. |
| ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
| WB | Western Blot Protocol |
| FC | Flow Cytometry Protocol |
| Target | Blood-brain barrier |
| Alternative Name | BBB |
