Anti-C5 Neutralizing Antibody (V3S-0522-YC7276) (CAT#: V3S-0522-YC7276)

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Datasheet

MSDS

COA

Sub Cat Target Species Isotype Application Affinity  
V3S-1124-YC340 Human IgG Neut; FuncS Inquiry
V3S-0622-YC1157 Human IgG ELISA; FC; IP; FuncS; IF; Neut; WB Inquiry
V3S-0822-YC445 Human IgG2a ELISA; Neut Inquiry
V3S-0822-YC447 Human IgG1 ELISA; Neut; WB Inquiry
V3S-0822-YC450 Human IgG2a ELISA; Neut Inquiry
V3S-0822-YC451 Human IgG1 Neut; WB; ELISA Inquiry
V3S-0822-YC452 Human IgG2a Neut; WB; ELISA; FuncS Inquiry
V3S-0822-YC453 Human IgG1 WB; ELISA; Neut Inquiry
V3S-1022-YC3289 Human IgG WB; ELISA; IF; IP; Block 0.03 nM Inquiry
Summary
Property
Applications
Protocols
Target

Summary

Description This product is a monoclonal antibody derived from Human (Homo sapiens), which can specifically recognize Complement component 5. The antibody is expressed with mammalian cell transient expression system, serum-free and purified by affinity chromatography. The purity and integrity are tested via SDS-PAGE and SEC-HPLC analysis. Given an antigen, additional QC measures are also desired such as affinity testing and binding validation.
Specifically, the antibody is provided in multiple formats for in vivo and in vitro assays. The Invivo version features greater than 95% purity, ultra-low endotoxin levels (<1 EU/mg or 0.1 EU/mg), and is preservative, stabilizer, and carrier protein-free.
Clonality Monoclonal
Host Species Human
Target Species Human
Immunogen Human complement component 5
Isotype IgG

Property

Expression Species HEK293F or CHO
Conjugation None
Purity >95%, determined by SDS-PAGE and/or SEC-HPLC
Endotoxin <1 EU/mg, determined by LAL method
Purification Protein A affinity purified
Sterility 0.2 μM filtered
Formulation PBS, pH 7.4
Preservation No preservatives
Stabilizer No stabilizers
Storage Store at 4⁰C within a week. For longer storage, aliquot and store at -20⁰C.

Applications

Application Neut; FuncS
Application Notes The antibody is recommended for detection of C5 by Neut, FuncS assays.

Protocols

ELISA Enzyme-Linked Immunosorbent Assay Protocol
WB Western Blot Protocol
FC Flow Cytometry Protocol

Target

Target C5
Alternative Name C5; complement component 5; C5D; C5a; C5b; ECLZB; CPAMD4; complement C5; prepro-C5; C5a anaphylatoxin; anaphylatoxin C5a analog; C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4
Gene ID 727
UniProt P01031
Research Area Immunology
For research use only, not directly for clinical use.
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