Recombinant Anti-CD274 Neutralizing Antibody (V3S-0622-YC70) (CAT#: V3S-0622-YC70)

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Datasheet

MSDS

COA

Sub Cat Target Species Isotype Application  
V3S-1124-YC709 Human, Mouse IgG ELISA; Block Inquiry
V3S-0622-YC71 Human, Mouse IgG ELISA; Block Inquiry
V3S-0622-YC72 Human IgG1 Block; FuncS; ELISA Inquiry
Summary
Property
Applications
Protocols
Target

Summary

Description This product is a human monoclonal antibody that specifically bind to PD-L1. The mAb was verified for binding on native cells expressing PD-L1. It can useful for inhibiting PD-L1-mediated immunosuppression and enhancing cell and cytokine mediated immunity involved in neoplastic and infectious diseases.
Clonality Monoclonal
Host Species Human
Target Species Human, Mouse
Isotype IgG

Property

Expression Species HEK293F or CHO
Conjugation None
Purity >95%, determined by SDS-PAGE and SEC-HPLC
Endotoxin <1 EU/mg
Purification Protein A affinity purified
Sterility 0.2 μM filtered
Formulation PBS, pH 7.4
Preservation No preservatives
Stabilizer No stabilizers
Storage Store at 4°C within a week. For longer storage, aliquot and store at -20°C.

Applications

Application ELISA; Block
Application Notes The antibody is recommended for detection of CD274 by ELISA, Block assays.

Protocols

ELISA Enzyme-Linked Immunosorbent Assay Protocol
WB Western Blot Protocol
FC Flow Cytometry Protocol

Target

Target CD274
Alternative Name B7-H; B7H1; PDL1; PD-L1; PDCD1L1; PDCD1LG1; programmed cell death 1 ligand 1; B7 homolog 1; CD274 antigen; PDCD1 ligand 1
Gene ID 29126
UniProt Q9NZQ7
Research Area Immunology
For research use only, not directly for clinical use.
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