Recombinant Anti-CD33 (ECD domain) Neutralizing Antibody (V3S-0622-YC77) (CAT#: V3S-0622-YC77)

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Datasheet

MSDS

COA

Summary
Property
Applications
Protocols
Target

Summary

Description This product is a human anti-CD33 antibody obtained from a high-capacity fully human leukemia phage antibody library. The antibody can specifically inhibit the growth of CD33 positive leukemia cell lines HL-60 and Kasumi-1. It has the advantages of low in immunogenicity and strong in specificity.
Clonality Monoclonal
Host Species Human
Target Species Human
Immunogen CD33-ECD protein
Epitope The epitope is located in the extracellular domain.
Isotype IgG

Property

Expression Species HEK293F or CHO
Conjugation None
Purity >95%, determined by SDS-PAGE and SEC-HPLC
Endotoxin <1 EU/mg
Purification Protein A affinity purified
Sterility 0.2 μM filtered
Formulation PBS, pH 7.4
Preservation No preservatives
Stabilizer No stabilizers
Storage Store at 4°C within a week. For longer storage, aliquot and store at -20°C.

Applications

Application ELISA; Inhib
Application Notes The antibody is recommended for detection of CD33 by ELISA, Inhib assays.

Protocols

ELISA Enzyme-Linked Immunosorbent Assay Protocol
WB Western Blot Protocol
FC Flow Cytometry Protocol

Target

Target CD33
Alternative Name p67; SIGLEC3; SIGLEC-3; myeloid cell surface antigen CD33; CD33 antigen (gp67); CD33 molecule transcript; gp67; sialic acid-binding Ig-like lectin 3
Gene ID 945
UniProt P20138
Related pathway Immune System; Immunoregulatory interaction
Research Area Immunology; Stem Cell
For research use only, not directly for clinical use.
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