| Description | The product is a distinctive anti-CD4 antibody that attaches to domain 2 of the extracellular section of the CD4 receptor. This effectively prevents the formation of HIV-induced syncytia, while still allowing for gp120 binding. Additionally, the antibody does not have any immunosuppressive effects. |
| Clonality | Monoclonal |
| Host Species | Human |
| Target Species | Human |
| Isotype | Human IgG4 |
| Expression Species | HEK293F or CHO |
| Conjugation | None |
| Purity | >95%, determined by SDS-PAGE and SEC-HPLC |
| Endotoxin | <1 EU/mg |
| Purification | Protein A affinity purified |
| Sterility | 0.2 μM filtered |
| Formulation | PBS, pH 7.4 |
| Preservation | No preservatives |
| Stabilizer | No stabilizers |
| Storage | Store at 4°C within a week. For longer storage, aliquot and store at -20°C. |
| Application | FC; Inhib; ELISA; WB; IHC |
| Application Notes | ELISA: 10 μg/mL |
| ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
| WB | Western Blot Protocol |
| FC | Flow Cytometry Protocol |
| Target | CD4 |
| Alternative Name | CD4 Molecule; T-Cell Surface Glycoprotein CD4; T-Cell Surface Antigen T4/Leu-3; CD4 Antigen (P55); CD4 Receptor; CD4 Antigen; CD4mut |
| Gene ID | 920 |
| UniProt | P01730 |
| Related pathway | Cancer Research |
| Research Area | Cancer Research |
| Related Disease | Infectious Disease and Cancer |
