Description | The product is a distinctive anti-CD4 antibody that attaches to domain 2 of the extracellular section of the CD4 receptor. This effectively prevents the formation of HIV-induced syncytia, while still allowing for gp120 binding. Additionally, teh antiboy does not have any immunosuppressive effects. |
Clonality | Monoclonal |
Host Species | Human |
Target Species | Human |
Isotype | Human IgG4 |
Expression Species | HEK293F or CHO |
Conjugation | None |
Purity | >95%, determined by SDS-PAGE and SEC-HPLC |
Endotoxin | <1 EU/mg |
Purification | Protein A affinity purified |
Sterility | 0.2 μM filtered |
Formulation | PBS, pH 7.4 |
Preservation | No preservatives |
Stabilizer | No stabilizers |
Storage | Store at 4°C within a week. For longer storage, aliquot and store at -20°C. |
Application | FC; Inhib; ELISA; WB; IHC |
Application Notes | ELISA: 10 μg/mL |
ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
WB | Western Blot Protocol |
FC | Flow Cytometry Protocol |
Target | CD4 |
Alternative Name | CD4 Molecule; T-Cell Surface Glycoprotein CD4; T-Cell Surface Antigen T4/Leu-3; CD4 Antigen (P55); CD4 Receptor; CD4 Antigen; CD4mut |
Gene ID | 920 |
UniProt | P01730 |
Related pathway | Cancer Research |
Research Area | Cancer Research |
Related Disease | Infectious Disease and Cancer |