| Description | Fab 6 is a broadly neutralizing antibody targeting the capsid protein of CPV and FPV, derived from mouse. It binds specifically with B site of capsid protein, which is about equidistant from the surrounding five-, three-, and twofold axes. It shows neutralization ability against CPV and FPV. This product has been determined by Enzyme-linked immunosorbent assay and Neutralization assay. |
| Clonality | Monoclonal |
| Host Species | Mouse |
| Target Species | Canine parvovirus (CPV), Feline parvovirus (FPV) |
| Immunogen | Capsids of CPV prepared from infected feline cells |
| Epitope | Site A near the top of the threefold spike. |
| Neutralization Mechanism | Bivalent attachment across an adjacent icosahedral twofold axis |
| Isotype | Mouse IgG |
| Expression Species | HEK293F or CHO cell line |
| Conjugation | Unconjugated |
| Purity | >95% |
| Endotoxin | <1 EU/mg |
| Form | Liquid |
| Purification | Protein G purified |
| Sterility | 0.2 μM filtered |
| Formulation | PBS, pH 7.4 |
| Preservation | No preservatives |
| Stabilizer | No stabilizers |
| Storage | Store at 4°C within one or two weeks. Store at -20°C for long term. Avoid repeated freeze/thaw cycles. Refer to the COA file for specifics. |
| Application | ELISA; Neut |
| ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
| WB | Western Blot Protocol |
| FC | Flow Cytometry Protocol |
| Target | CPV / FPV capsid protein |
| Alternative Name | Canine parvovirus capsid protein, Feline panleukopenia virus capsid protein |
| Research Area | Infectious Disease |
| Related Disease | Acute gastrointestinal illness |
