| Description | This is a humanized monoclonal antibody that binds specifically to human GM-CSF with high affinity. The antibody can cross react with macaca GM-CSF. It has Inhibition of GM-CSF induced TF-1 proliferation. |
| Clonality | Monoclonal |
| Host Species | Human |
| Target Species | Human, Macaca |
| Epitope | Interacts with hGM-CSF through one key residue at position 117. |
| Affinity | 4 pM for human GM-CSF I117, 7 pM for human GM-CSF T117, 11 pM for macaca GM-CSF |
| Isotype | Human IgG |
| Expression Species | HEK293F or CHO |
| Conjugation | None |
| Purity | >95%, determined by SDS-PAGE and SEC-HPLC |
| Endotoxin | <1 EU/mg |
| Purification | Protein A affinity purified |
| Sterility | 0.2 μM filtered |
| Formulation | PBS, pH 7.4 |
| Preservation | No preservatives |
| Stabilizer | No stabilizers |
| Storage | Store at 4°C within a week. For longer storage, aliquot and store at -20°C. |
| Application | Inhib |
| ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
| WB | Western Blot Protocol |
| FC | Flow Cytometry Protocol |
| Target | CSF2 |
| Alternative Name | Colony Stimulating Factor 2; Molgramostin; Colony Stimulating Factor 2 (Granulocyte-Macrophage); GMCSF; CSF |
| Gene ID | 1437 |
| UniProt | P04141 |
| Related pathway | MIF Mediated Glucocorticoid Regulation and Gene expression (Transcription) |
| Research Area | Autophagy |
| Related Disease | Autoimmune or inflammatory disease |
