| Sub Cat | Target Species | Isotype | Application | Affinity | |
|---|---|---|---|---|---|
| V3S-1124-YC643 | Human, Rhesus | IgG | Inhib; ELISA | 0.53 nM (25 °C), 0.34 nM (37 °C) | |
| V3S-1022-YC1423 | Human | IgG1 kappa | ELISA | 1.24 nM |
| Description | This is a human monoclonal antibody that targets against IP-10. It cross-reacts with human and rhesus monkey. The antibody shows different binding affinity for human IP-10, with a affinity of 0.53 nM at 25 °C and 0.34 nM at 37 °C. |
| Clonality | Monoclonal |
| Host Species | Human |
| Target Species | Human, Rhesus |
| Immunogen | Purified recombinant human IP10 |
| IC50 | 1.25 for HPBL, 0.18 for 300.19 cells |
| EC50 | 40 ng/mL for human, 80 ng/mL for monkey |
| Affinity | 0.53 nM for 25 °C; 0.34 nM for 37 °C |
| Isotype | Human IgG |
| Expression Species | HEK293F or CHO |
| Conjugation | None |
| Purity | >95%, determined by SDS-PAGE and SEC-HPLC |
| Endotoxin | <1 EU/mg |
| Purification | Protein A affinity purified |
| Sterility | 0.2 μM filtered |
| Formulation | PBS, pH 7.4 |
| Preservation | No preservatives |
| Stabilizer | No stabilizers |
| Storage | Store at 4°C within a week. For longer storage, aliquot and store at -20°C. |
| Application | Inhib; ELISA |
| ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
| WB | Western Blot Protocol |
| FC | Flow Cytometry Protocol |
| Target | CXCL10 |
| Alternative Name | C-X-C Motif Chemokine Ligand 10; Small Inducible Cytokine Subfamily B (Cys-X-Cys), Member 10; 10 KDa Interferon Gamma-Induced Protein; Chemokine (C-X-C Motif) Ligand 10; Small-Inducible Cytokine B10; SCYB10; INP10; IP-10; Protein 10 From Interferon (Gamma)-Induced Cell Line; Interferon-Inducible Cytokine IP-10 |
| Gene ID | 3627 |
| UniProt | P02778 |
| Related pathway | MIF Mediated Glucocorticoid Regulation and GPCR downstream signalling |
| Research Area | Signal Pathway |
| Related Disease | Spotted Fever and Cryptosporidiosis |
