| Description | This is a human IgG2 monoclonal antibody that binds specifically to human CXCL12. It targets the epitope of P10 and Q48, optionally one or more of K54 and N45. The antibody has an affinity for CXCL12 with a KD of 3.7 nM. |
| Clonality | Monoclonal |
| Host Species | Human |
| Target Species | Human |
| Epitope | P10 and Q48, optionally one of more of K54 and N45 |
| Affinity | KD = 3.7 nM |
| Isotype | Human IgG2 |
| Expression Species | HEK293F or CHO |
| Conjugation | None |
| Purity | >95%, determined by SDS-PAGE and SEC-HPLC |
| Endotoxin | <1 EU/mg |
| Purification | Protein A affinity purified |
| Sterility | 0.2 μM filtered |
| Formulation | PBS, pH 7.4 |
| Preservation | No preservatives |
| Stabilizer | No stabilizers |
| Storage | Store at 4°C within a week. For longer storage, aliquot and store at -20°C. |
| Application | Inhib |
| ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
| WB | Western Blot Protocol |
| FC | Flow Cytometry Protocol |
| Target | CXCL12 |
| Alternative Name | C-X-C Motif Chemokine Ligand 12; Pre-B Cell Growth-Stimulating Factor; Chemokine (C-X-C Motif) Ligand 12; Intercrine Reduced In Hepatomas; Stromal Cell-Derived Factor 1; SDF1; PBSF; IRH; C-X-C Motif Chemokine 12 |
| Gene ID | 6387 |
| UniProt | P48061 |
| Related pathway | Apoptotic Pathways in Synovial Fibroblasts and MIF Mediated Glucocorticoid Regulation |
| Research Area | Signal Pathway |
| Related Disease | Human Immunodeficiency Virus Type 1 and Ischemia |
