Description | A therapeutic monoclonal antibody (mAb), known as EDIIImAb-61, has been developed to specifically target the domain III of the envelope glycoprotein (EDIII) of the DENV virus. This antibody has the remarkable capability to detect and bind to all four DENV serotypes (DENV-1 to DENV-4), making it a versatile therapeutic option. |
Clonality | Monoclonal |
Host Species | Mouse |
Target Species | Dengue Virus (DENV) |
Immunogen | Fusion of rEDIII protein with SP2/0-Ag14 myeloma cells |
Epitope | The domain III of the envelope glycoprotein |
Isotype | IgG1 |
Expression Species | HEK293F or CHO cell line |
Conjugation | Unconjugated |
Purity | >95% |
Endotoxin | <1 EU/mg |
Form | Liquid |
Purification | Protein G purified |
Sterility | 0.2 μM filtered |
Formulation | PBS, pH 7.4 |
Preservation | No preservatives |
Stabilizer | No stabilizers |
Storage | Store at 4°C within one or two weeks. Store at -20°C for long term. Avoid repeated freeze/thaw cycles. Refer to the COA file for specifics. |
Application | IF; ELISA; Neut |
ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
WB | Western Blot Protocol |
FC | Flow Cytometry Protocol |
Target | DENV |
Alternative Name | Dengue virus; DENV |
Research Area | Microbiology |