| Description | This product is a human monoclonal antibody that reacts with human ERBB2 protein. The antibody 71F10 showed moderate binding cross-reactivity to mouse ErbB2. 71F10 also showed cross-reactivity with rat ErbB2. |
| Clonality | Monoclonal |
| Host Species | Human |
| Target Species | Human, Cynomolgus, Mouse, Rat |
| Immunogen | Recombinant human HER2 ectodomain |
| Epitope | The epitope is located in the extracellular domain. |
| Isotype | IgG1 kappa |
| Expression Species | HEK293F or CHO |
| Conjugation | None |
| Purity | >95%, determined by SDS-PAGE and SEC-HPLC |
| Endotoxin | <1 EU/mg |
| Purification | Protein A affinity purified |
| Sterility | 0.2 μM filtered |
| Formulation | PBS, pH 7.4 |
| Preservation | No preservatives |
| Stabilizer | No stabilizers |
| Storage | Store at 4°C within a week. For longer storage, aliquot and store at -20°C. |
| Application | ELISA; FC; FuncS |
| Application Notes | The antibody is recommended for detection of ERBB2 by ELISA, FC, FuncS assays. |
| ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
| WB | Western Blot Protocol |
| FC | Flow Cytometry Protocol |
| Target | ERBB2 |
| Alternative Name | NEU; NGL; HER2; TKR1; CD340; HER-2; MLN 19; HER-2/neu; receptor tyrosine-protein kinase erbB-2; c-erb B2/neu protein; herstatin; human epidermal growth factor receptor 2; metastatic lymph node gene 19 protein; neuro/glioblastoma derived oncogene homolog; neuroblastoma/glioblastoma derived oncogene homolog; p185erbB2; proto-oncogene Neu; proto-oncogene c-ErbB-2; tyrosine kinase-type cell surface receptor HER2; v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2; v-erb-b2 avian erythroblastic leukemia viral oncoprotein 2; v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog |
| Gene ID | 2064 |
| UniProt | P04626 |
| Related pathway | mitogen-activated protein kinase (MAPK); phosphoinositide 3-kinase (PI3K/Akt); phospholipase C γ; protein kinase C (PKC); Signal transducer and activator of transcription (STAT) |
| Research Area | Signal Pathway |
