| Description | This product is a human monoclonal antibody that binds to human tissue factor and demonstrate enhanced ADCC activity. The mAb is a highly effective inhibitor of tumor incidence, growth and progression. It can be used in a variety of methods for diagnosing diseases involving tissue factor, where enhanced ADCC activity is desirable such as cancer. |
| Clonality | Monoclonal |
| Host Species | Human |
| Target Species | Human |
| Isotype | IgG4 kappa |
| Expression Species | HEK293F or CHO |
| Conjugation | None |
| Purity | >95%, determined by SDS-PAGE and SEC-HPLC |
| Endotoxin | <1 EU/mg |
| Purification | Protein A affinity purified |
| Sterility | 0.2 μM filtered |
| Formulation | PBS, pH 7.4 |
| Preservation | No preservatives |
| Stabilizer | No stabilizers |
| Storage | Store at 4°C within a week. For longer storage, aliquot and store at -20°C. |
| Application | FuncS |
| Application Notes | The antibody is recommended for detection of F3 by FuncS assay. |
| ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
| WB | Western Blot Protocol |
| FC | Flow Cytometry Protocol |
| Target | F3 |
| Alternative Name | Coagulation Factor III, Tissue Factor; Coagulation Factor III (Thromboplastin, Tissue Factor); Tissue Factor; TF; Coagulation Factor III; Thromboplastin; CD142 Antigen; CD142; TFA; CNTO-859; CNTO 859 |
| Gene ID | 2152 |
| UniProt | P13726 |
| Related pathway | Blood coagulation pathway |
| Research Area | Cardiovascular |
