Anti-HBV preS1 Neutralizing Antibody (V3S-0723-FY210) (CAT#: V3S-0723-FY210)

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Datasheet

MSDS

COA

Summary
Property
Applications
Protocols
Target

Summary

Description The antibody is a human recombinant antibody that specifically targets the preS1 region of the Hepatitis B Virus (HBV). The antibody has demonstrated a broad neutralization activity against two other HBV genotypes, namely B and C. The IC₅₀ values for genotype B, C, and D are 80 pM, 30 pM, and 10 pM, respectively. Additionally, the clone was evaluated for its ability to neutralize six HBV genotype C viruses obtained from plasma samples of HBV-infected patients. The antibody exhibited significantly higher potency compared to HBIG in neutralizing these viruses, with at least several hundred to 1000-fold greater effectiveness.
Clonality Monoclonal
Host Species Human
Target Species Hepatitis B Virus genotype B, C, and D
Isotype IgG1

Property

Expression Species HEK293F or CHO cell line
Conjugation Unconjugated
Purity >95%
Endotoxin <1 EU/mg
Form Liquid
Purification Protein A purified
Sterility 0.2 μM filtered
Formulation PBS, pH 7.4
Preservation No preservatives
Stabilizer No stabilizers
Storage Store at 4°C within one or two weeks. Store at -20°C for long term. Avoid repeated freeze/thaw cycles. Refer to the COA file for specifics.

Applications

Application ELISA; WB; Neut; ADCC
Application Notes The IC₅₀ values of the antibody for genotype B, C, and D are 80 pM, 30 pM, and 10 pM, respectively.

Protocols

ELISA Enzyme-Linked Immunosorbent Assay Protocol
WB Western Blot Protocol
FC Flow Cytometry Protocol

Target

Target HBV preS1
Alternative Name Hepatitis B Virus preS1; preS1; Hepatitis B Virus; HBV
Research Area Microbiology
For research use only, not directly for clinical use.
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