| Description | The antibody was isolated from non-human primates (NHPs) immunized with variants derived from the tier 2 clade C 16055 strain. It interacts with the hypervariable V2 region. And it displays neutralizing activity against the autologous virus with potency 0.13 μg/mL (IC₅₀). This product has been detected by Enzyme-linked immunosorbent assay and Neutralization assay. |
| Clonality | Monoclonal |
| Host Species | Monkey |
| Target Species | HIV-1 16055 WT |
| Immunogen | Variants of NFL HIV-1 Env trimers derived from the tier 2 clade C 16055 strain |
| Epitope | V1V2 domain |
| Neutralization Mechanism | It interacts with the hypervariable V2 region |
| IC50 | 0.13 μg/mL |
| Isotype | IgG |
| Expression Species | HEK293F or CHO cell |
| Purity | >95%, determined by SDS-PAGE and SEC-HPLC |
| Endotoxin | <1 EU/mg |
| Form | Liquid |
| Purification | Protein A purified |
| Sterility | 0.2 μM filtered |
| Formulation | PBS, pH 7.4 |
| Preservation | No preservatives |
| Stabilizer | No stabilizers |
| Storage | Store at 4°C within one or two weeks. Store at -20°C for long term. Avoid repeated freeze/thaw cycles. Refer to the COA file for specifics. |
| Application | ELISA; Neut |
| Application Notes | Neutralization assay (Neut): The IC₅₀ value of this antibody against 16055 WT is 0.13 μg/mL. |
| ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
| WB | Western Blot Protocol |
| FC | Flow Cytometry Protocol |
| Target | HIV-1 gp160 |
| Alternative Name | Human immunodeficiency virus type 1 glycoprotein 160 |
| Research Area | Infectious Disease |
| Related Disease | Acquired Immune Deficiency Syndrome |
