| Description | This antibody specifically targets HIV gp120 and is derived from a cattle antibody, the NC-Cow1 clone exhibited a 72% neutralization breadth against a panel of 117 viruses, with a half-maximal inhibitory concentration (IC₅₀) of 0.028 ug/ml. |
| Clonality | Monoclonal |
| Host Species | Cattle |
| Target Species | Human immunodeficiency virus (HIV) |
| Immunogen | HIV envelope (Env) trimer BG505 SOSIP.664 |
| Neutralization Breath | 72% |
| IC50 | 0.028 μg/mL |
| Isotype | Cattle IgG |
| Expression Species | HEK293F or CHO |
| Conjugation | None |
| Purity | >95%, determined by SDS-PAGE and SEC-HPLC |
| Endotoxin | <1 EU/mg |
| Purification | Protein G purified |
| Sterility | 0.2 μM filtered |
| Formulation | PBS, pH 7.4 |
| Preservation | No preservatives |
| Stabilizer | No stabilizers |
| Storage | Store at 4°C within a week. For longer storage, aliquot and store at -20°C. |
| Application | ELISA; Neut |
| ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
| WB | Western Blot Protocol |
| FC | Flow Cytometry Protocol |
| Target | HIV gp120 |
| Alternative Name | HIV envelope; HIV; envelope; HIV-1; gp120; human immunodeficiency virus |
| Research Area | Microbiology |