| Description | This product is a rabbit neutralizing antibody clone HTN-Gn1, which targeting the Hantaan virus glycoprotein Gn (HTNV Gn). It binds residues in the loop that links HTNV Gn strands β4 and β5. HTN-Gn1 modestly neutralized live Hantaan virus in vitro. This product has been detected by Enzyme-linked immunosorbent assay and Neutralization assay. |
| Clonality | Monoclonal |
| Host Species | Rabbit |
| Target Species | Hantaan virus (HTNV) |
| Immunogen | Recombinantly derived Gn from Hantaan virus |
| Epitope | Residues 82 to 96 in the loop that links HTNV Gn strands β4 and β5. |
| Expression Species | HEK293F or CHO cell line |
| Conjugation | Unconjugated |
| Purity | >95% |
| Endotoxin | <1 EU/mg |
| Form | Liquid |
| Purification | Protein A purified |
| Sterility | 0.2 μM filtered |
| Formulation | PBS, pH 7.4 |
| Preservation | No preservatives |
| Stabilizer | No stabilizers |
| Storage | Store at 4°C within one or two weeks. Store at -20°C for long term. Avoid repeated freeze/thaw cycles. Refer to the COA file for specifics. |
| Application | ELISA; Neut |
| Application Notes | The ELISA and Neutralization assay were implemented to test the quality of Ab. For ELISA, the Ab started at 20 μg/mL with a serial 1:5 dilution. The Neutralization assay' results indicated that Ab HTN-Gn1 modestly neutralized live virus in vitro with an IC50 of 15.47 μg/mL. |
| ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
| WB | Western Blot Protocol |
| FC | Flow Cytometry Protocol |
| Target | HTNV Gn |
| Alternative Name | Hantaan virus glycoprotein Gn |
| Research Area | Infectious Disease |
| Related Disease | Hemorrhagic fever |
