| Description | This product is a IAV HA1 broadly neutralizing human antibody. The V110P-A117E mutation maintains high-affinity binding to these heterosubtypic strains. While the mutants V110P and V110P-A117E show improved binding affinity against viruses A/Puerto Rico/8/1934 and A/mallard/35/1976, the variant antibodies and the WT failed to inhibit hemagglutination of these two viruses. |
| Clonality | Monoclonal |
| Host Species | Human |
| Target Species | Influenzavirus A (IAV) |
| Immunogen | Influenza a virus Hemagglutinin protein |
| Isotype | Human IgG |
| Expression Species | HEK293F or CHO |
| Conjugation | None |
| Purity | >95%, determined by SDS-PAGE and SEC-HPLC |
| Endotoxin | <1 EU/mg |
| Purification | Protein A purified |
| Sterility | 0.2 μM filtered |
| Formulation | PBS, pH 7.4 |
| Preservation | No preservatives |
| Stabilizer | No stabilizers |
| Storage | Store at 4°C within a week. For longer storage, aliquot and store at -20°C. |
| Application | ELISA; Neut |
| ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
| WB | Western Blot Protocol |
| FC | Flow Cytometry Protocol |
| Target | IAV HA1 |
| Alternative Name | Influenza A virus Hemagglutinin; Influenza A virus; Hemagglutinin; HA; IAV |
| Research Area | Microbiology |
