Anti-IL18 Neutralizing Antibody (V3S-0522-YC2367) (CAT#: V3S-0522-YC2367)

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Datasheet

MSDS

COA

Sub Cat Target Species Isotype Application Affinity  
V3S-1124-YC342 Human, Monkey IgG2 Neut 92 pM Inquiry
V3S-0622-YC278 Human, Cynomolgus IgG1 kappa ELISA; Neut; IP; FC 0.196 nM Inquiry
V3S-0822-YC1608 Human IgA2 Neut Inquiry
V3S-1022-YC1814 Human, Rhesus IgG1 kappa ELISA; Neut 0.03 nM Inquiry
V3S-1022-YC1815 Human, Rhesus IgG1 kappa ELISA; Neut 0.014 nM Inquiry
V3S-0522-YC2366 Human IgG ELISA Inquiry
V3S-0522-YC7798 Human IgG WB; ELISA; FuncS Inquiry
V3S-1022-YC1318 Human IgG ELISA 30.3 pM Inquiry
V3S-1022-YC2902 Human IgG lambda WB; ELISA Inquiry
V3S-1022-YC702 Human IgG ELISA Inquiry
V3S-1022-YC703 Human, Rhesus IgG2 Inhib 9.96 nM Inquiry
V3S-1022-YC704 Human, Rhesus IgG2 Inhib 0.5 nM Inquiry
Summary
Property
Applications
Protocols
Target

Summary

Description This product is a monoclonal antibody derived from Human (Homo sapiens), which can specifically recognize Interleukin 18 (interferon-gamma-inducing factor). The antibody is expressed with mammalian cell transient expression system, serum-free and purified by affinity chromatography. The purity and integrity are tested via SDS-PAGE and SEC-HPLC analysis. Given an antigen, additional QC measures are also desired such as affinity testing and binding validation.
Specifically, the antibody is provided in multiple formats for in vivo and in vitro assays. The Invivo version features greater than 95% purity, ultra-low endotoxin levels (<1 EU/mg or 0.1 EU/mg), and is preservative, stabilizer, and carrier protein-free.
Clonality Monoclonal
Host Species Human
Target Species Human, Monkey
Affinity KD = 92 pM, determined by surface plasmon resonance.
Isotype IgG2

Property

Expression Species HEK293F or CHO
Conjugation None
Purity >95%, determined by SDS-PAGE and/or SEC-HPLC
Endotoxin <1 EU/mg, determined by LAL method
Purification Protein A affinity purified
Sterility 0.2 μM filtered
Formulation PBS, pH 7.4
Preservation No preservatives
Stabilizer No stabilizers
Storage Store at 4⁰C within a week. For longer storage, aliquot and store at -20⁰C.

Applications

Application Neut
Application Notes The antibody is recommended for detection of IL18 by Neut assay.

Protocols

ELISA Enzyme-Linked Immunosorbent Assay Protocol
WB Western Blot Protocol
FC Flow Cytometry Protocol

Target

Target IL18
Alternative Name IGIF; IL-18; IL-1g; IL1F4
Gene ID 3606
UniProt Q14116
Research Area Immunology; Cancer Research
Related Disease Inflammatory, Cardiovascular, Autoimmune disease
For research use only, not directly for clinical use.
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