Anti-ITGB2 Neutralizing Antibody (V3S-0522-YC200) (CAT#: V3S-0522-YC200)

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Datasheet

MSDS

COA

Sub Cat Isotype Application  
V3S-1124-YC1388 IgG1 kappa ELISA; WB; Block Inquiry
V3S-0622-YC1965 IgG Neut; ELISA; IF; IP; FuncS; FC; IHC Inquiry
V3S-1022-YC1735 IgG1 Block Inquiry
V3S-1022-YC1514 IgG ELISA Inquiry
Summary
Property
Applications
Protocols
Target

Summary

Description This product is a monoclonal antibody derived from Human (Homo sapiens), which can specifically recognize Integrin subunit beta 2. The antibody is expressed with mammalian cell transient expression system, serum-free and purified by affinity chromatography. The purity and integrity are tested via SDS-PAGE and SEC-HPLC analysis. Given an antigen, additional QC measures are also desired such as affinity testing and binding validation.
Specifically, the antibody is provided in multiple formats for in vivo and in vitro assays. The Invivo version features greater than 95% purity, ultra-low endotoxin levels (<1 EU/mg or 0.1 EU/mg), and is preservative, stabilizer, and carrier protein-free.
Clonality Monoclonal
Host Species Human
Target Species Human
Isotype IgG1, κ

Property

Expression Species HEK293F or CHO
Conjugation None
Purity >95%, determined by SDS-PAGE and/or SEC-HPLC
Endotoxin <1 EU/mg, determined by LAL method
Purification Protein A affinity purified
Sterility 0.2 μM filtered
Formulation PBS, pH 7.4
Preservation No preservatives
Stabilizer No stabilizers
Storage Store at 4⁰C within a week. For longer storage, aliquot and store at -20⁰C.

Applications

Application ELISA; WB; Block
Application Notes The antibody is recommended for detection of ITGB2 by ELISA, WB, Block assays.

Protocols

ELISA Enzyme-Linked Immunosorbent Assay Protocol
WB Western Blot Protocol
FC Flow Cytometry Protocol

Target

Target ITGB2
Alternative Name LAD; CD18; MF17; MFI7; LCAMB; LFA-1; MAC-1
Gene ID 3689
UniProt P05107
Research Area Signal Pathway
Related Disease Leukocyte adhesion deficiency (LAD)
For research use only, not directly for clinical use.
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