Anti-JAG1 Neutralizing Antibody (V3S-0622-YC305) (CAT#: V3S-0622-YC305)

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Datasheet

MSDS

COA

Sub Cat Application Affinity  
V3S-1124-YC591 ELISA; Inhib; FuncS 0.3 nM Inquiry
V3S-0622-YC306 ELISA; Inhib; FuncS Inquiry
V3S-1022-YC3174 ELISA; IF; Block 0.71 nM Inquiry
V3S-1022-YC3175 ELISA; IF; Block 2.6 nM Inquiry
Summary
Property
Applications
Protocols
Target

Summary

Description This product is a human monoclonal antibody that reacts with JAG1. The antibody is expressed with mammalian cell transient expression system, serum-free and purified by affinity chromatography. The purity and integrity are tested via SDS-PAGE and SEC-HPLC analysis. Given an antigen, additional QC measures are also desired such as affinity testing and binding validation.
Specifically, the antibody is provided in multiple formats for in vivo and in vitro assays. The Invivo version features greater than 95% purity, ultra-low endotoxin levels (<1 EU/mg or 0.1 EU/mg), and is preservative, stabilizer, and carrier protein-free.
Clonality Monoclonal
Host Species Human
Target Species Human, Mouse
Affinity 0.3 nM
Isotype IgG1

Property

Expression Species HEK293F or CHO
Conjugation None
Purity >95%, determined by SDS-PAGE and/or SEC-HPLC
Endotoxin <1 EU/mg, determined by LAL method
Purification Protein A affinity purified
Sterility 0.2 μM filtered
Formulation PBS, pH 7.4
Preservation No preservatives
Stabilizer No stabilizers
Storage Store at 4⁰C within a week. For longer storage, aliquot and store at -20⁰C.

Applications

Application ELISA; Inhib; FuncS
Application Notes The antibody is recommended for detection of JAG1 by ELISA, Inhib, FuncS assays.

Protocols

ELISA Enzyme-Linked Immunosorbent Assay Protocol
WB Western Blot Protocol
FC Flow Cytometry Protocol

Target

Target JAG1
Alternative Name Jagged1; AGS; AHD; AWS; HJ1; AGS1; DCHE; CD339; JAGL1; Protein jagged-1
Gene ID 182
UniProt P78504
Research Area Cardiovascular; Neuroscience
For research use only, not directly for clinical use.
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