Description | The GPC-B antibody 18.5C-M30 binds quaternary epitopes on the prefusion conformation of GP. The GPC-B MAb recognizes a quaternary epitope bridging two neighboring monomers at the GP2 base of the trimer. |
Clonality | Monoclonal |
Host Species | Human |
Target Species | Lassa virus (LASV) |
Epitope | Spanning two adjacent monomers and bridging their GP1 to GP2 subunits |
IC50 | 3.24 nM (Neutralization of ppVSV-LASV LI ) |
Isotype | Human IgG |
Expression Species | HEK293F or CHO cell line |
Conjugation | Unconjugated |
Purity | >95% |
Endotoxin | <1 EU/mg |
Form | Liquid |
Purification | Protein A purified |
Sterility | 0.2 μM filtered |
Formulation | PBS, pH 7.4 |
Preservation | No preservatives |
Stabilizer | No stabilizers |
Storage | Store at 4°C within one or two weeks. Store at -20°C for long term. Avoid repeated freeze/thaw cycles. Refer to the COA file for specifics. |
Application | ELISA; BLI; Neut |
ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
WB | Western Blot Protocol |
FC | Flow Cytometry Protocol |
Target | LASV GPC |
Alternative Name | Lassa virus glycoprotein precursor |
Research Area | Infectious Disease |
Related Disease | Lassa hemorrhagic fever |