| Description | The GPC-B antibody 18.5C-M30 binds quaternary epitopes on the prefusion conformation of GP. The GPC-B MAb recognizes a quaternary epitope bridging two neighboring monomers at the GP2 base of the trimer. |
| Clonality | Monoclonal |
| Host Species | Human |
| Target Species | Lassa virus (LASV) |
| Epitope | Spanning two adjacent monomers and bridging their GP1 to GP2 subunits |
| IC50 | 3.24 nM (Neutralization of ppVSV-LASV LI ) |
| Isotype | Human IgG |
| Expression Species | HEK293F or CHO cell line |
| Conjugation | Unconjugated |
| Purity | >95% |
| Endotoxin | <1 EU/mg |
| Form | Liquid |
| Purification | Protein A purified |
| Sterility | 0.2 μM filtered |
| Formulation | PBS, pH 7.4 |
| Preservation | No preservatives |
| Stabilizer | No stabilizers |
| Storage | Store at 4°C within one or two weeks. Store at -20°C for long term. Avoid repeated freeze/thaw cycles. Refer to the COA file for specifics. |
| Application | ELISA; BLI; Neut |
| ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
| WB | Western Blot Protocol |
| FC | Flow Cytometry Protocol |
| Target | LASV GPC |
| Alternative Name | Lassa virus glycoprotein precursor |
| Research Area | Infectious Disease |
| Related Disease | Lassa hemorrhagic fever |