Description | This product is a human antibody recognizing LCMV GP (Lymphocytic choriomeningitis virus surface glycoprotein), termed as 18.5C-M28. It locks the glycoprotein in the pre-fusion state to prevent viral entry. 18.5C-M28 neutralizes lymphocytic choriomeningitis virus in vitro and prophylactically and therapeutically protects mice from chronic LCMV infection. It has been tested by Enzyme-linked immunosorbent assay, Bio-layer interferometry and Neutralization assay. |
Clonality | Monoclonal |
Host Species | Human |
Target Species | Lymphocytic choriomeningitis virus (LCMV) |
Isotype | Human IgG |
Expression Species | HEK293F or CHO cell line |
Conjugation | Unconjugated |
Purity | >95% |
Endotoxin | <1 EU/mg |
Form | Liquid |
Purification | Protein A purified |
Sterility | 0.2 μM filtered |
Formulation | PBS, pH 7.4 |
Preservation | No preservatives |
Stabilizer | No stabilizers |
Storage | Store at 4°C within one or two weeks. Store at -20°C for long term. Avoid repeated freeze/thaw cycles. Refer to the COA file for specifics. |
Application | ELISA; BLI; Neut |
ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
WB | Western Blot Protocol |
FC | Flow Cytometry Protocol |
Target | LCMV GP |
Alternative Name | lymphocytic choriomeningitis virus glycoprotein |
Research Area | Infectious Disease |
Related Disease | severe birth defects |