| Description | This product is a human monoclonal antibody that reacts with LINGO1. The antibody is expressed with mammalian cell transient expression system, serum-free and purified by affinity chromatography. The purity and integrity are tested via SDS-PAGE and SEC-HPLC analysis. Given an antigen, additional QC measures are also desired such as affinity testing and binding validation. Specifically, the antibody is provided in multiple formats for in vivo and in vitro assays. The Invivo version features greater than 95% purity, ultra-low endotoxin levels (<1 EU/mg or 0.1 EU/mg), and is preservative, stabilizer, and carrier protein-free. |
| Clonality | Monoclonal |
| Host Species | Human |
| Target Species | Human |
| Isotype | IgG |
| Expression Species | HEK293F or CHO |
| Conjugation | None |
| Purity | >95%, determined by SDS-PAGE and/or SEC-HPLC |
| Endotoxin | <1 EU/mg, determined by LAL method |
| Purification | Protein A affinity purified |
| Sterility | 0.2 μM filtered |
| Formulation | PBS, pH 7.4 |
| Preservation | No preservatives |
| Stabilizer | No stabilizers |
| Storage | Store at 4⁰C within a week. For longer storage, aliquot and store at -20⁰C. |
| Application | FuncS |
| Application Notes | The antibody is recommended for detection of LINGO1 by FuncS assay. |
| ELISA | Enzyme-Linked Immunosorbent Assay Protocol |
| WB | Western Blot Protocol |
| FC | Flow Cytometry Protocol |
| Target | LINGO1 |
| Alternative Name | LINGO1; leucine rich repeat and Ig domain containing 1; LERN1; LRRN6A; UNQ201; leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1; leucine rich repeat neuronal 6A; leucine-rich repeat neuronal protein 1; leuc |
| Gene ID | 84894 |
| UniProt | Q96FE5 |
| Related pathway | p75 NTR receptor-mediated signalling; Signaling by GPCR |
| Research Area | Neuroscience |
