Recombinant Anti-LRP6 (ECD domain) Antibody (V3S-0622-YC3630) (CAT#: V3S-0622-YC3630)

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Description This product is a human monoclonal antibody that reacts with LRP6. The antibody is expressed with mammalian cell transient expression system, serum-free and purified by affinity chromatography. The purity and integrity are tested via SDS-PAGE and SEC-HPLC analysis. Given an antigen, additional QC measures are also desired such as affinity testing and binding validation.
Specifically, the antibody is provided in multiple formats for in vivo and in vitro assays. The Invivo version features greater than 95% purity, ultra-low endotoxin levels (<1 EU/mg or 0.1 EU/mg), and is preservative, stabilizer, and carrier protein-free.
Clonality Monoclonal
Host Species Human
Target Species Human
Immunogen A combination of LRP6 proteins consisting of recombinant LRP6-Fc protein and/or LRP6 extracellular domain (ECD).
Epitope Within the ECD domain.
Affinity 4.11 nM
Isotype IgG1 kappa


Expression Species HEK293F or CHO
Conjugation None
Purity >95%, determined by SDS-PAGE and/or SEC-HPLC
Endotoxin <1 EU/mg, determined by LAL method
Purification Protein A affinity purified
Sterility 0.2 μM filtered
Formulation PBS, pH 7.4
Preservation No preservatives
Stabilizer No stabilizers
Storage Store at 4⁰C within a week. For longer storage, aliquot and store at -20⁰C.


Application ELISA; FC
Application Notes The antibody is recommended for detection of LRP6 by ELISA, FC assays.


ELISA Enzyme-Linked Immunosorbent Assay Protocol
WB Western Blot Protocol
FC Flow Cytometry Protocol


Target LRP6
Alternative Name LRP6; low density lipoprotein receptor-related protein 6; ADCAD2; low-density lipoprotein receptorrelated protein 6; LRP-6
Gene ID 4040
UniProt O75581
Related pathway Canonical Wnt pathway
Research Area Signal Pathway; Stem Cell
For research use only, not directly for clinical use.
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