Anti-MCAM Neutralizing Antibody (V3S-0723-FY221) (CAT#: V3S-0723-FY221)

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Datasheet

MSDS

COA

Summary
Property
Applications
Protocols
Target

Summary

Description Hu1749H3L3 is a humanized antibody that specifically targets Human MCAM. It exhibits a high binding affinity of 0.221 nM towards human MCAM. The antibody possesses the valuable ability to inhibit the binding of MCAM to the laminin a4 chain of laminin 411.
Clonality Monoclonal
Host Species Human
Target Species Human
Affinity 0.221 nM
Isotype IgG1, kappa

Property

Expression Species HEK293F or CHO cell line
Conjugation Unconjugated
Purity >95%
Endotoxin <1 EU/mg
Form Liquid
Purification Protein A purified
Sterility 0.2 μM filtered
Formulation PBS, pH 7.4
Preservation No preservatives
Stabilizer No stabilizers
Storage Store at 4°C within one or two weeks. Store at -20°C for long term. Avoid repeated freeze/thaw cycles. Refer to the COA file for specifics.

Applications

Application FC; ELISA; Block

Protocols

ELISA Enzyme-Linked Immunosorbent Assay Protocol
WB Western Blot Protocol
FC Flow Cytometry Protocol

Target

Target MCAM
Alternative Name Melanoma Cell Adhesion Molecule; S-Endo 1 Endothelial-Associated Antigen; Melanoma-Associated Antigen MUC18; Cell Surface Glycoprotein P1H12; Melanoma-Associated Antigen A32; Gicerin
Gene ID 4162
UniProt P43121
Research Area Immunology; Signal Pathway
For research use only, not directly for clinical use.
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